Introduction
This Ultimate Giant Muffaletta Sandwich Recipe is a show-stopping centerpiece for any gathering. Inspired by the classic New Orleans flavors, it layers savory Italian meats, tangy olive salad, and melted cheese on a giant, toasted loaf. For another impressive main dish, try the Grilled Flank Steak with Balsamic Caprese Twist Recipe. It’s perfect for feeding a crowd with bold, unforgettable taste.
Ingredients
Building this Giant Muffaletta Italian Sandwich starts with gathering its bold, savory components, where the tangy olive salad and layers of cured meats and cheese create a truly unforgettable flavor experience.
- 1 large 10-inch round Italian bread loaf
- 2 cups olive salad (mix of green and black olives, giardiniera, roasted red peppers, capers, garlic, oregano, olive oil, and vinegar)
- ½ lb capicola or deli ham, thinly sliced
- ½ lb Genoa salami, thinly sliced
- ½ lb mortadella, thinly sliced
- ½ lb sliced provolone cheese
- ½ lb sliced mozzarella cheese

Timing
| Prep Time | 25 minutes |
| Cook Time | 5 minutes |
| Total Time | 30 minutes |
Context: This streamlined assembly for a Giant Muffaletta Italian Sandwich is about 20% faster than similar recipes that require extensive marinating or baking.
Step-by-Step Instructions
Step 1 — Prepare the Olive Salad
Combine 1 cup each of chopped green and black olives with ½ cup giardiniera, ¼ cup chopped roasted red peppers, 2 minced garlic cloves, 2 tbsp capers, and ¼ cup olive oil. Mix well and let it marinate for at least 30 minutes to allow the flavors to meld.
Tip: For the best flavor, make the olive salad a day ahead and store it covered in the refrigerator.
Step 2 — Slice and Prepare the Bread
Use a large, round loaf of Italian bread or a muffaletta roll. Slice it horizontally to create a top and bottom half. Gently pull out some of the soft interior bread from both halves to create a well for the fillings.
This step prevents your Giant Muffaletta Italian Sandwich from becoming too bready and ensures every bite is packed with flavor.
Step 3 — Layer the First Meats and Cheeses
On the bottom half of the bread, start with a layer of thinly sliced Genoa salami, followed by a layer of sliced provolone cheese. The fat from the salami will help create a moisture barrier against the bread.
Step 4 — Add the Olive Salad
Spoon half of your prepared olive salad evenly over the cheese layer. Press it down gently so the oils and juices begin to soak into the bread and cheese below.
Step 5 — Continue with Remaining Meats and Cheese
Add layers of thinly sliced ham, mortadella, and capicola. Top this with another layer of provolone and the remaining half of the olive salad.
Tip: Keep slices thin and arrange them evenly, slightly overlapping, to ensure consistent flavor and easy slicing later.
Step 6 — Assemble and Wrap Tightly
Place the top half of the bread on the mound of fillings and press down firmly. Wrap the entire Giant Muffaletta Italian Sandwich tightly in several layers of plastic wrap.
Step 7 — Press and Rest
Place the wrapped sandwich on a tray or baking sheet. Put a heavy skillet or a few cans on top to weigh it down. Let it press at room temperature for at least 1 hour, or refrigerate for 3-4 hours for deeper flavor infusion.
This pressing step is crucial—it compresses the ingredients so the sandwich holds together and the flavors marry perfectly.
Step 8 — Slice and Serve
Unwrap the sandwich and use a long, sharp serrated knife to cut it into wedges or quarters. For the classic presentation, cut the round loaf into four large wedges.
Your Giant Muffaletta Italian Sandwich is now ready to serve. It can be enjoyed immediately or kept wrapped for up to a day, as the flavors continue to improve.
Nutritional Information
| Calories | ~850 kcal |
| Protein | ~42 g |
| Carbohydrates | ~68 g |
| Fat | ~45 g |
| Fiber | ~6 g |
| Sodium | ~2100 mg |
Note: Nutritional values for this Giant Muffaletta Italian Sandwich are estimates based on typical ingredients and serving size. Actual values can vary depending on specific brands and preparation methods.
Healthier Alternatives
Enjoy the bold flavors of a Giant Muffaletta Italian Sandwich with these simple, practical ingredient swaps.
- Leaner Protein — Swap traditional salami and mortadella for sliced roasted turkey or chicken breast. You’ll get the savory satisfaction with significantly less saturated fat.
- Lower-Carb Option — For a low-carb Giant Muffaletta Italian Sandwich, serve the filling over a bed of crisp greens or stuff it into large, sturdy lettuce leaves like romaine hearts.
- Gluten-Free Bread — Use a high-quality, sturdy gluten-free round loaf or focaccia. Toasting it lightly helps prevent sogginess from the olive salad.
- Dairy-Free Cheese — Omit the provolone or use a plant-based mozzarella or provolone-style cheese alternative that melts well.
- Low-Sodium Pickle Power — Rinse the giardiniera and olives thoroughly before chopping for the olive salad to wash away excess brine, dramatically cutting the sodium.
- Lighter Olive Salad — Make your olive salad with more chopped celery, roasted red peppers, and fresh herbs, using less olive oil for a brighter, lighter condiment.
- Whole-Grain Boost — Use a whole-wheat or seeded Italian round loaf for added fiber and nutrients while keeping the classic sandwich structure.
- Reduced-Fat Meats — Look for “lower sodium” or “natural casing” versions of classic deli meats, which often contain fewer preservatives and less fat.

Serving Suggestions
- For a classic New Orleans-style picnic, serve your Giant Muffaletta Italian Sandwich with a side of zesty red beans and rice and a crisp, cold beer.
- Cut this hearty sandwich into wedges for easy sharing at game-day gatherings, potlucks, or casual parties.
- Pair it with light, crunchy sides to balance its richness, like a tangy Italian chopped salad, garlicky potato chips, or pickled vegetables.
- Elevate a casual lunch by plating a wedge alongside a small bowl of warm tomato bisque for dipping.
- For the ultimate feast, present the whole Giant Muffaletta Italian Sandwich on a large wooden board surrounded by olives, pepperoncini, and marinated artichoke hearts.
- Let the assembled sandwich rest, wrapped tightly, for at least an hour before slicing. This allows the flavors to marry and the bread to soften perfectly.
No matter how you serve it, this iconic Giant Muffaletta Italian Sandwich is a show-stopping centerpiece meant for sharing and savoring.
Common Mistakes to Avoid
- Mistake: Using a soft, fluffy bread that collapses under the weight of the fillings. Fix: Choose a sturdy, round loaf like a ciabatta or a true muffaletta roll that can absorb juices without getting soggy.
- Mistake: Skipping the olive salad or not letting it marinate. Fix: Make the olive giardiniera at least a day ahead so the flavors meld and properly season the entire sandwich.
- Mistake: Layering meats and cheeses haphazardly. Fix: Create even, overlapping layers of each cured meat and cheese to ensure every bite has the full, balanced flavor profile.
- Mistake: Building and serving the sandwich immediately. Fix: Wrap the assembled Giant Muffaletta Italian Sandwich tightly and press it under weight for 1-2 hours so the flavors marry and the texture becomes perfect.
- Mistake: Overloading with wet ingredients that make the bread soggy. Fix: Drain your olive salad and roasted peppers well, and consider brushing the bread interior with a little olive oil as a moisture barrier.
- Mistake: Using only one type of meat or a low-quality deli selection. Fix: Invest in a variety of high-quality cured meats like mortadella, Genoa salami, and capicola for authentic, complex flavor.
- Mistake: Cutting the sandwich into small pieces too soon. Fix: Let the pressed sandwich rest whole, then cut it into large wedges just before serving to keep the interior juicy and intact.
- Mistake: Neglecting the spread. Fix: Blend some of the marinated olive salad into a coarse paste to spread on both halves of the bread, creating a flavor base in every bite.
- Mistake: Serving it cold from the fridge. Fix: Bring your Giant Muffaletta Italian Sandwich to cool room temperature for about 30 minutes before serving to allow the fats to soften and flavors to bloom.
Storing Tips
- Fridge: Wrap the assembled Giant Muffaletta Italian Sandwich tightly in plastic wrap or foil and refrigerate for up to 3 days. The olive salad will keep the bread moist, but for best texture, store components separately in airtight containers.
- Freezer: For longer storage, wrap the whole sandwich or individual portions tightly in plastic wrap and then aluminum foil. Freeze for up to 1 month. Thaw overnight in the refrigerator before serving.
- Reheat: For a warm sandwich, wrap it in foil and bake at 325°F (160°C) until the internal temperature reaches 165°F (74°C), about 20-25 minutes. You can also reheat individual slices in a skillet over medium-low heat to crisp the bread.
Always use airtight containers or heavy-duty wraps to prevent the strong flavors from permeating other foods in your fridge or freezer. For food safety, do not leave the sandwich at room temperature for more than 2 hours.
Conclusion
This Giant Muffaletta Italian Sandwich is the ultimate centerpiece for any gathering. We hope you love this bold, shareable recipe as much as we do. Give it a try and let us know what you think in the comments! For more hearty favorites, check out our Reuben Bake Recipe with Corned Beef and Sauerkraut or Sun-Dried Tomato, Spinach, and Ricotta Grilled Cheese Recipe.
PrintGiant Muffaletta Italian Sandwich
A massive New Orleans-style muffaletta sandwich featuring a large round Italian loaf stuffed with layers of Italian meats, cheeses, and tangy olive salad for the ultimate party sandwich.
- Author: Dorothy Miller
- Prep Time: 20 minutes
- Cook Time: 0 minutes
- Total Time: 1 hour 20 minutes (including pressing)
- Yield: 8 1x
- Method: Main Dish
- Cuisine: Italian-American
Ingredients
- 1 large 10-inch round Italian bread loaf
- 2 cups olive salad (mix of green and black olives, giardiniera, roasted red peppers, capers, garlic, oregano, olive oil, and vinegar)
- ½ lb capicola or deli ham, thinly sliced
- ½ lb Genoa salami, thinly sliced
- ½ lb mortadella, thinly sliced
- ½ lb sliced provolone cheese
- ½ lb sliced mozzarella cheese
Instructions
- Slice the round bread loaf in half horizontally and open it on a flat surface. Brush both inner sides generously with olive oil from the olive salad or extra virgin olive oil.
- Layer the meats and cheeses on the bottom half: start with capicola or ham, followed by Genoa salami, mortadella, provolone, and mozzarella.
- Spread 1 cup of olive salad over the layered meats and cheeses, then top with the remaining 1 cup of olive salad on the top half of the bread.
- Place the top half of the bread over the filling and press down firmly. Wrap tightly in plastic wrap, place a heavy object on top, and refrigerate for 1-2 hours to compress.
- Unwrap and slice into 6-8 large wedges using a serrated bread knife. Serve cold or at room temperature.
Notes
Prepare the olive salad a day ahead for best flavor infusion. Use high-quality deli meats sliced thin for easier layering. This giant sandwich serves a crowd perfectly for parties.
Nutrition
- Calories: 850
- Sugar: 5g
- Sodium: 2800mg
- Fat: 60g
- Saturated Fat: 18g
- Unsaturated Fat: 35g
- Trans Fat: 0g
- Carbohydrates: 45g
- Fiber: 4g
- Protein: 35g
- Cholesterol: 95mg
FAQs
What is the best bread for a Giant Muffaletta Italian Sandwich?
The classic choice is a large, round, soft Italian loaf or a sturdy sesame-topped roll. The bread should be soft enough to press but sturdy enough to hold the substantial fillings and olive salad without becoming soggy. This structure is key for an authentic Giant Muffaletta Italian Sandwich.
Can I make the olive salad ahead of time?
Yes, preparing the olive salad a day or two in advance is highly recommended. This allows the flavors to meld and intensify, which greatly enhances the overall taste of your Giant Muffaletta Italian Sandwich. Store it covered in the refrigerator until you are ready to assemble.
How long can I store a prepared sandwich?
Once assembled, wrap the entire Giant Muffaletta Italian Sandwich tightly in plastic wrap. It can be refrigerated for several hours or overnight, which actually helps the flavors combine. For best texture, let it sit at room temperature for about 30 minutes before slicing and serving.



